一、个人简介：
张莹，教授，博士生导师。海南医科大学基础医永盈会体育投注病原生物学专业老师，现任中国免疫学会兽医免疫分会常务委员；中国畜牧兽医学会动物传染病学会青年委员。主要从事流感病毒进化与致病机制、跨宿主感染、抗原变异、新型疫苗等基础和应用研究。研究成果发表在Science、Emerging Microbes & Infections 、Nature Microbiology、Plos Pathogens、 Journal of Virology 等高水平SCI期刊。
二、教育和工作经历：
2026.03－至今：海南医科大学教授
2016.11- 2026.03：沈阳农业大学 动物科学与医学永盈会体育投注，三级教授。博士生/硕士生导师
2013.11-2016.10：美国威斯康辛大学麦迪逊分校 兽医永盈会体育投注流感研究所，博士后
2012.11-2013.10: 美国密西根州立大学 微生物与分子遗传永盈会体育投注，博士后
2009.9-2012.7: 中国农业科永盈会体育投注研究生院 预防兽医学，博士
2006.9-2009.7: 中国农业科永盈会体育投注研究生院 预防兽医学，硕士
2001.9-2006.7: 沈阳农业大学动物医永盈会体育投注 动物医学，学士
三、主要研究方向： 流感病毒分子流行病学与病原生态学；流感病毒表型相关分子机制；重组病毒载体疫苗研制等研究。
四、主要科研项目：
1. 国家自然科学基金，面上项目，野鸟流感病毒稳定性特征对哺乳动物宿主适应性的影响，32570623，51万，2026-01-01至2029-12-31
2. 国家重点研发计划，动物疫病综合防控关键技术研发与应用专项，子课题，病原生态对流感病毒致病与传播表型影响，2021YFD1800203，275万，2021-05-01至2025-12-31
3. 国家自然科学基金，面上项目，病原生态对野鸟流感病毒传播的影响，32170539，57万，2022-01-01至2025-12-31
4.国家自然科学基金，青年项目，H13N8亚型野鸟流感病毒跨宿主感染机制研究，32000357，24万，2021-01-01至2023-12-31
五、代表性论著：
1.Weiwei Ma, Chenyang Ren, Lin Shi, Bo Meng, Yali Feng, Ying Zhang，Isoleucine at position 137 of haemagglutinin acts as a mammalian adaptation marker of H9N2 avian influenza virus，Emerging Microbes & Infections, 2025, 14(1):2455597
2.Siqi Tang, Yaoqi Wang, Xiaorui Zhang, Hailing Li, Haoyu Leng, Yali Feng, Ying Zhang, Co-circulation of H3N2 canine influenza and distemper viruses in canine populations from Liaoning, China, Journal of Integrative Agriculture, 2025, DOI: 10.1016/j.jia.2025.08.006
3.Siqi Tang, Bing Han, Chaofan Su, Hailing Li, Shiyuchen Zhao, Haoyu Leng, Yali Feng, Ying Zhang, Wild Bird-Origin H6N2 Influenza Virus Acquires Enhanced Pathogenicity after Single Passage in Mice, Viruses, 2024, 16(3):357
4.Bo Meng, Qian Wang, Haoyu Leng, Chenyang Ren, Chong Feng, Weiwei Guo, Yali Feng, Ying Zhang, Evolutionary Events Promoted Polymerase Activity of H13N8 Avian Influenza Virus, Viruses, 2024, 16(3):329
5.Yina Xu, Hailing Li, Haoyu Leng, Chaofan Su, Siqi Tang, Yongtao Wang, Shiwei Zhang, Yali Feng, Yanan Wu, Daxin Wang, Ying Zhang, Genetic and Biological Properties of H10Nx influenza viruses in China, Journal of Integrative Agriculture, 2024, 23(11):3860-3869
6.Bo Meng, Hailing Li, Chong Feng , Weiwei Guo , Yali Feng , Dawei Zhu , Hualan Chen, Ying Zhang, Emergence of a novel reassortant H3N6 canine influenza virus, Frontiers in Microbiology, 2023, 14:1186869
7.YU Si-hui, SHAN Zhao-meng, YANG Jing-jing , LIU Yi-ning , WU Chang-de , ZHANG Zhen-jiang , ZHU Yuan-mao , MENG Bo , ZHAN Jia-xing , WEN Xue-xia, ZHANG Ying, Identification of two novel linear epitopes on the p30 protein of African swine fever virus, Journal of Integrative Agriculture, 2023, 22(6):1945-1949
8.Yanting Du, Chen Wang, Ying Zhang, Viral Coinfections, Viruses, 2022, 14(12):2645
9.Hailing Li, Haoyu Leng, Siqi Tang, Chaofan Su, Yina Xu, Yongtao Wang, Jiaming Lv, Shiwei Zhang, Yali Feng, Shaokang Song, Ying Zhang, Prevalence, Genetics and Evolutionary Properties of Eurasian Avian-like H1N1 Swine Influenza Viruses in Liaoning, Viruses, 2022, 14(12):2645
10. Weiwei Ma, Chenyang Ren, Qingbiao Hu, Xiaodong Li, Yali Feng, Ying Zhang, Freshwater crabs could act as vehicles of spreading avian influenza virus, Virology Journal, 2021, 18(1):246
11. Yuhang Sun,Jinlong Zhang, Zixuan Liu, Ying Zhang*, Kehe Huang*, Swine Influenza Virus Infection Decreases the Protective Immune Responses of Subunit Vaccine Against Porcine Circovirus Type 2, Frontiers in Microbiology, 2021, 12:807458
12. Xuexia Wen#, Xijun He#, Xiang Zhang, Xianfeng Zhang, Liling Liu, Yuntao Guan, Ying Zhang*, Zhigao Bu*, Genome sequences derived from pig and dried blood pig feed samples provide important insights into the transmission of African swine fever virus in China in 2018, Emerging Microbes & Infections, 2019, 8(1): 303
13. Chengjun Li#, Masato Hatta#, David F. Burke#, Jihui Ping#, Ying Zhang#, Makoto Ozawa, Andrew S. Taft, Subash C. Das, Anthony P. Hanson, Jiasheng Song, Masaki Imai, Peter R. Wilker, Tokiko Watanabe, Shinji Watanabe, Mutsumi Ito, Kiyoko Iwatsuki-Horimoto, Colin A. Russell, Sarah L. James, Eugene Skepner, Eileen A. Maher, Gabriele Neumann, Alexander I. Klimov, Anne Kelso, John McCauley, Dayan Wang, Yuelong Shu, Masato Tashiro, Nancy J. Cox, Derek J. Smith, and Yoshihiro Kawaoka. Selection of antigenically advanced variants of seasonal influenza viruses. Nature Microbiology, 2016, 1(6)16058
14. Ying Zhang#, Qianyi Zhang#, Huihui Kong, Yongping Jiang, Yuwei Gao, Guohua Deng, Jianzhong Shi, Guobin Tian, Liling Liu, Jinxiong Liu, Yuntao Guan, Zhigao Bu, Hualan Chen. H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet. Science, 2013, 340(6139):1459-63
15. Ying Zhang, Qianyi Zhang, Yuwei Gao, Xijun He, Huihui Kong, Yongping Jiang, Yuntao Guan, Xiazhu Xia, Yuelong Shu, Yoshihiro Kawaoka, Zhigao Bu, and Hualan Chen. Key molecular factors in HA and PB2 contribute to the efficient transmission of the 2009 H1N1 pandemic influenza virus. Journal of Virology, 2012, 86(18):9666-9674 Spotlight article
16. Yuwei Gao, Ying Zhang, Kyoko Shinya, Guohua Deng, Yongping Jiang, Zejun Li, Yuntao Guan, Guobin Tian, Yanbing Li, Jianzhong Shi, Liling Liu, Xianying Zeng, Zhigao Bu, Xianzhu Xia, Yoshihiro Kawaoka, Hualan Chen. Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host. PLoS Pathogens, 2009, 5(12): e1000709
六、承担项目：
1.国家自然科学基金，面上项目，野鸟流感病毒稳定性特征对哺乳动物宿主适应性的影响，32570623，51万，2026-01-01至2029-12-31
2.国家重点研发计划，动物疫病综合防控关键技术研发与应用专项，子课题，病原生态对流感病毒致病与传播表型影响，2021YFD1800203，275万，2021-05-01至2025-12-31
3.国家自然科学基金，面上项目，病原生态对野鸟流感病毒传播的影响，32170539，57万，2022-01-01至2025-12-31
4.国家自然科学基金，青年项目，H13N8亚型野鸟流感病毒跨宿主感染机制研究，32000357，24万，2021-01-01至2023-12-31
5.辽宁省重点研发项目，动物流感防控新技术研究，2020JH2/10200035，30万，2020-05-01至2023-04-30
6.兴辽英才”青年拔尖人才，盘锦湿地野鸟流感病原生态系统研究，XLYC2007114，50万，2021-01-01至2023-12-31
7.辽宁省教育厅，外泌体在牛结节性皮肤病病毒感染中的功能研究，JYTYB2024068，5万，2024-06-01至2026-05-31
七、学术组织兼职：中国免疫学会兽医免疫分会常务委员；中国畜牧兽医学会动物传染病学会青年委员
八、获得奖励：入选“千人计划”青年项目、“兴辽英才”青年拔尖人才、“辽宁百千万人才”百层次人才。
九、联系方式： vetzhangying@126.com
